Measurement of urinary total LDH activity and its isoenzyme fractionation has been suggested to be a useful means of diagnosis and follow-up the course of urinary tract diseases. The normal value of Korean healthy adults has not been established, so authors have studied the normal range of urinary total LDH activity and its isoen-zymes in Korean healthy adults.
The results are as follows.
1) The total urinary LDH activity in 114 cases is 21.4+2.8 (S. E.) U/L.
2) In 114 cases, only 38 cases (30%) could be fractionated. The average percentage of each LDH isoenzymes are that LDH-1; 33.2+6.7%, LDH-2; 27.4+5.6%, LDH-3; 17.3+3.0%, LDH-4; 11.0+4.3%, LDH-5; 11.1+9.0%, respectively. There is no differences between male and female about each fraction. (p>0.05)
3) Storage of the samples, the results decrease as time passes and show significant differences at room temprature. (p<0.05) The result within 24 hrs is 24.7 + 16.3 U/L, that after 24 hr5 is 16.3 + 9.2 U/L, that after 48 hrs is 15.6 + 7.6 U/L.
4) The results make no differences though the concentration procedure applied. (p>0.05)
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